Conolidine is often a purely natural alkaloid derived in the bark in the tropical shrub Tabernaemontana divaricata, also known as crepe jasmine. This shrub was usually Utilized in Chinese, Ayurvedic, and Thai drugs, which is common for its powerful suffering-relieving Houses.Szpakowska et al. also analyzed conolidone and its action on the ACKR3 rec